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For a tiny segment of the population, extra-skinny jeans may cause “tingling thigh syndrome.” The condition, known as meralgia paresthetica, "can happen when constant pressure — in Ghoman's case, from the skin-tight denim — cuts off the lateral femoral cutaneous nerve, causing a numb, tingling or burning sensation along the thigh." The never damage isn't permanent, and can be repaired with a few weeks of strict boyfriend-jeans-only wear. [NBC Bay Area]